研究業績

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Shinjyo N., Kimura H., Yoshihara T., Suzuki J., Yamaguchi M., Kawabata S., & Okabe Y.

Aldehyde metabolism ensures mucociliary clearance in oxidative airway injury

Research Square, https://doi.org/10.21203/rs.3.rs-5067166/v1 (2024)

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Okabe Y.

Development and organization of omental milky spots

Immunological Reviews, http://doi.org/10.1111/imr.13337 (2024)

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Luca D., Lee S., Hirota K., Okabe Y., Uehori J., Izawa K., Lanz AL., Schütte V., Sivri B., Tsukamoto Y., Hauck F., Behrendt R., Roers A., Fujita T., Nishikomori R., Lee-Kirsch MA., & Kato H.

Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity

Science Advance, eadk0820. doi: 10.1126/sciadv.adk0820 (2024)

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Yoshihara T., & Okabe Y.

Aldh1a2+ fibroblastic reticular cells regulate lymphocyte recruitment in omental milky spots

The Journal of Experimental Medicine, 220(5), e20221813 (2023)

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Okabe Y.

Immune Niche Within the Peritoneal Cavity

Current Topics in Microbiology and Immunology, 434, 123-134 (2021)

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Ohteki T., & Okabe Y.

The Origins of Macrophages and Their Roles Beyond Immunology

International Immunology, 30(11), 483-484 (2018)

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Okabe Y.

Molecular control of the identity of tissue-resident macrophages

International Immunology, 30(11), 485-491 (2018)

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Okabe Y., & Medzhitov R.

Wormhole Travel for Macrophages

Cell, 165(3), 518-519 (2016)

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Okabe Y., & Medzhitov R.

Tissue Biology Perspective on Macrophages

Nature Immunology, 17, 9-17 (2016)

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Okabe Y., & Medzhitov R.

How the immune system spots tumors

Elife, 3, (2014)

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Okabe Y., & Medzhitov R.

Tissue-specific signals control reversible program of localization and functional polarization of macrophages

Cell, 157, 832-844 (2014)   Cell, Best of 2014に選出

 

Okabe Y., Sano T.(equal contribution), & Nagata S.

Regulation of the innate immune response by threonine-phosphatase of Eyes absent

Nature, 460, 520-524 (2009)

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Okabe Y., Kawane K., & Nagata S.

IFN regulatory factor (IRF) 3/7-dependent and –independent gene induction by mammalian DNA that escapes degradation

European Journal of Immunology, 38, 3150-3158 (2008)

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Nakaya M., Tanaka M., Okabe Y., Hanayama R., & Nagata S.

Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages

The Journal of Biological Chemistry, 281, 8836-8842 (2006)

 

Okabe Y., Kawane K., Akira S., Taniguchi T., & Nagata S.

Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

The Journal of Experimental Medicine, 202, 1333-1339 (2005)

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Yoshida H., Okabe Y.(equal contribution), Kawane K., Fukuyama H., & Nagata S.

Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

Nature Immunology, 6, 49-56 (2005)

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Takahasi K., Suzuki N., Horiuchi M., Mori M., Suhara W., Okabe Y., Fukuhara Y., Terasawa H., Akira S., Fujita T., & Inagaki F.

X-ray crystal structure of IRF-3 and its functional implications

Nature Structual & Molecular Biology, 10, 922-927 (2003)

 

Iwamura T., Yoneyama M., Koizumi N., Okabe Y., Namiki H., Samuel CE., & Fujita T.

PACT, a Double-Stranded RNA Binding Protein Acts as a Positive Regulator for Type I Interferon Gene Induced by Newcastle Disease Virus

Biochemical and Biophysical Research Communications, 282, 515-523 (2001)

 

Iwamura T., Yoneyama M., Yamaguchi K., Suhara W., Mori W., Shiota K., Okabe Y., Namiki H., & Fujita T.

Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways

Genes to Cells, 6, 375-388 (2001)